After playing six home games in their last seven all-competition outings Clarke's side face their first league away game in over a month as they travel the short distance to Vale Park where they take on Play-Off chasing Vale.
Managed by John Askey, the Valiants are ninth in League Two and are unbeaten at home so far this season, giving them plenty of belief heading into their meeting with the Saddlers.
Walsall boss Clarke admits that he is expecting Askey's side to pose a tough test but insists the Reds will go into the match full of confidence after rebounding from going two goals down to snatch victory in the fourth-minute of second-half injury time against a well-drilled Chalese U21s side.
Speaking via the club's official website, Darrell said; "They have a bit of stability now, they've done ok, had a reasonable start. But like I keep saying, the lines in League Two are very small. Teams at the top can easily be beaten, no problem about that.
"So we just keep focusing. We know it'll be a tough game, they have a decent home record but we go there with plenty of confidence. It's set up for a normal League Two encounter, we want to go there and be positive and try and win the game."