The clash, which is scheduled to take place at Banks’s Stadium, was in doubt as the Silkmen are currently struggling with financial issues which has seen their players go on strike over unpaid wages.
The strike saw last weekend’s clash with Crewe Alexandra suspended by the EFL, with Macclesfield owner Amar Alkadhi said to be in talks over takeover to end the crisis.
A statement released via the club's official website on Tuesday said: "Following a number of queries regarding Saturday’s scheduled home fixture with Macclesfield Town, the club can confirm that we have spoken with the EFL and the message is that the game is going ahead.
"As such all planning and preparation will continue as normal. If there is an update we will share this with you at the earliest opportunity."
Macclesfield have endured a series of off-field issues, including an ongoing winding-up petition filed by HM Revenue & Customs that has received the backing of former manager Sol Campbell, the 45-year-old ex-England defender is owed £180,000 by the club.