Managed by the ever-popular Karl Robinson, Oxford arrive at this weekend's match in the midst of a fifteen game unbeaten run and will no-doubt be keen to add the Saddlers to their list of victims by the time the referee blows for full-time on Saturday.
Walsall will also head into the match with an unbeaten record as Clarke, who has guided his team through the last five games without defeat, is hoping his side can get themselves into the hat for the Third Round draw.
The Mansfield-born manager is fully aware that the Saddlers will go into the game as underdogs, but he hoping that his squad will embrace the occasion and the magic of the cup with a potential money-spinning tie to come down the line.
Speaking via the club's official website, Darrell said; "Oxford have got that momentum that we all crave in football. They’re unbeaten in fifteen games and have scored a lot of goals in the process and they’ll be pretty confident but it’s the FA Cup.
"We’ll go into the game as the underdogs, we’re at home and I am sure our fans will be well up for it and we’re looking forward to the challenge. The pressure is never off with me, whether we’re in the league or in the cup, it’ll always be there.
"I enjoy the pressure and so should my players. We’re looking to see if we can get ourselves into the third round of the cup, which everyone wants to do and get that luxury tie but we have got a very tough game on our hands and we appreciate that.
"Oxford will come here with plenty of fans but we will be looking to upset the odds. There is a potential revenue there for the club if we get through but we have to draw ourselves away from that if we can.
"We have got to focus on the game that is in front of us. We could get through and get drawn a rubbish draw but we need to focus on the game and focus on getting ourselves into the hat for the next round and we can only do that by beating Oxford.
"We have to make sure that we perform on the day. We go into the game as slight underdogs and it’s an occasions that we have got to try and enjoy."